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Mindfulness courses : effects on physical, mental, social and cognitive health

I was recently asked to write a one-pager that summarises the evidence in support of mindfulness courses. This is no small feat, as there are thousands of peer-reviewed scientific papers reporting the effects of various formats of mindfulness-based interventions (MBIs) for physical, mental, cognitive and social health. I've had a quick go ... hopefully you'll find this of interest!


An article published in 2017 by Professor David J Creswell, of Carnegie Melon University provides an excellent starting point. In Mindfulness Interventions [1], Creswell assesses the strength and quality of evidence for MBIs in each of these health domains. I have drawn heavily on Creswell's findings and augmented with more recent evidence.


A bit about the terminology. I refer throughout to mindfulness-based interventions (MBIs). These are courses or programs of activity that teach the skills and practices of mindfulness. The evidence reported below is (except where stated) based on randomised controlled trials (RCTs). This is a type of study that collects data for pre-defined outcomes (like stress, mindfulness, markers of physical health, cognitive function, etc) from a study sample before and after an MBI. Importantly, the RCT sample involves at least two groups of people with similar characteristics and contexts; one does the MBI, the other group does not, and instead acts as the control group. Control groups for MBI research can be active (e.g. other psychological treatments, physical exercise, etc) or inactive (e.g. treatment as usual). RCTs give the best evidence of causality, because the differences between the two groups at the end of the training can be attributed to the MBI. Meta analyses and systematic reviews pool together the findings from multiple RCTs to show the overall level of effectiveness of MBIs across different settings, samples and contexts.


MBIs and physical health: MBI participants experience improved chronic pain management relative to usual treatment. Results from MBI studies showed effects superior to some active treatments (support groups, health education programs) and equivalent to others (e.g. cognitive behaviour therapy, CBT). Since 2021, MBIs have been an evidence-based first-line intervention tool for improving physical and psychological wellbeing in CVD patients[2]. There is also promising evidence that mindfulness interventions may improve immunity, reduce symptoms and improve quality of life across a broad range of stress-related conditions (e.g., fibromyalgia, IBS, breast cancer, psoriasis). At the time of publishing this article, relatively little is known about how MBIs affect health behaviours.


MBIs and mental health: MBI participants experience reduced depression relapse rates and substance use, and improved adherence to treatment for drug addiction. Reductions in anxiety, depression, and PTSD symptomatology are commonly reported following MBI participation. In some clinical contexts, MBIs can offer similar or additional long-term benefits compared to gold- standard treatments (e.g., antidepressants, relapse prevention programs, CBT). When offered as a non-clinical intervention in workplace settings, MBIs consistently improve stress and related mental health problems[3].


MBIs, cognition and mood: MBIs can improve attention-related outcomes (e.g., sustained attention, working memory) and affective outcomes (e.g., reducing rumination) in students and the skills and practices of mindfulness are commonly applied in school systems. MBIs also consistently appear to cultivate positive psychological capital (a composite of hope, self-efficacy, resilience and optimism)[4], which is associated with positive leadership, problem solving and performance in workplace contexts. Trait mindfulness has been shown to be associated with less cognitive decline and less Aβ and tau in the brain in older adults at risk for Alzheimer’s Disease[5] however evidence of changes in these markers in response to MBIs is limited[6]


MBIs, social and cultural outcomes: There is an emerging body of research on interpersonal and prosocial effects of MBIs, with studies pointing to improved relational outcomes (e.g., relationship satisfaction and prosocial behaviours). This has been shown in patient-clinician, student-teacher, parent-child and intimate partner settings[7]. Emerging evidence supports mindfulness interventions for cultivating adaptive leadership and workplace psychosocial safety[8]; and higher mindfulness as a sociocultural typology is associated with progress toward sustainable development goals at national levels[9].


Clearly the benefits of MBIs across physical, mental, social and cognitive domains are based in evidence. At this point in time the strongest evidence is in support of the standardized 8-week MBI training protocols (Mindfulness Based Stress Reduction and Mindfulness Based Cognitive Therapy) for improving mental health, followed by physical health, then social, cultural and cognitive outcomes.


I encourage you to check the reference list below if you’d like to take deeper dive into what has been very briefly mentioned above.


Larissa Bartlett PhD

April 24, 2024


-- REFERENCES --

[1] Creswell JD. Mindfulness Interventions. Annu Rev Psychol. 2017 Jan 3;68:491-516. doi: 10.1146/annurev-psych-042716-051139. Epub 2016 Sep 28. PMID: 27687118.

[2] Marino F, Failla C, Carrozza C, Ciminata M, Chilà P, Minutoli R, Genovese S, Puglisi A, Arnao AA, Tartarisco G, Corpina F, Gangemi S, Ruta L, Cerasa A, Vagni D, Pioggia G. Mindfulness-Based Interventions for Physical and Psychological Wellbeing in Cardiovascular Diseases: A Systematic Review and Meta-Analysis. Brain Sci. 2021 May 29;11(6):727. doi: 10.3390/brainsci11060727. PMID: 34072605; PMCID: PMC8227381.

[3] Bartlett L, Martin A, Neil AL, Memish K, Otahal P, Kilpatrick M, Sanderson K. A systematic review and meta-analysis of workplace mindfulness training randomized controlled trials. J Occup Health Psychol. 2019 Feb;24(1):108-126. doi: 10.1037/ocp0000146. PMID: 30714811.

[4] Roche M, Haar JM, Luthans F. The role of mindfulness and psychological capital on the well-being of leaders. J Occup Health Psychol. 2014 Oct;19(4):476-89. doi: 10.1037/a0037183. Epub 2014 Jun 16. PMID: 24933594.

[5] Strikwerda-Brown C, Ozlen H, Pichet Binette A, Chapleau M, Marchant NL, Breitner JCS, Villeneuve S. Trait Mindfulness Is Associated With Less Amyloid, Tau, and Cognitive Decline in Individuals at Risk for Alzheimer's Disease. Biol Psychiatry Glob Open Sci. 2022 Jan 17;3(1):130-138. doi: 10.1016/j.bpsgos.2022.01.001. PMID: 36712573; PMCID: PMC9874144.

[6] Schlosser M, Demnitz-King H, Barnhofer T, Collette F, Gonneaud J, Chételat G, Jessen F, Kliegel M, Klimecki OM, Lutz A, Marchant NL; Medit-Ageing Research Group. Effects of a mindfulness-based intervention and a health self-management programme on psychological well-being in older adults with subjective cognitive decline: Secondary analyses from the SCD-Well randomised clinical trial. PLoS One. 2023 Dec 15;18(12):e0295175. doi: 10.1371/journal.pone.0295175. PMID: 38100477; PMCID: PMC10723715.

[7] Singh NN, Lancioni GE, Winton AS, Curtis WJ, Wahler RG, Sabaawi M, Singh J, McAleavey K. Mindful staff increase learning and reduce aggression in adults with developmental disabilities. Res Dev Disabil. 2006 Sep-Oct;27(5):545-58. doi: 10.1016/j.ridd.2005.07.002. Epub 2005 Sep 26. PMID: 16188424.

[8] Roussel L. Leadership's Impact on Quality, Outcomes, and Costs. Crit Care Nurs Clin North Am. 2019 Jun;31(2):153-163. doi: 10.1016/j.cnc.2019.02.003. Epub 2019 Apr 8. PMID: 31047090.

[9] GBD 2019 Under-5 Mortality Collaborators. Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019. Lancet. 2021 Sep 4;398(10303):870-905. doi: 10.1016/S0140-6736(21)01207-1. Epub 2021 Aug 17. PMID: 34416195; PMCID: PMC8429803.

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